Study Examines MRI-Based Iron Measurements
July 11, 2013 – A study recently published in the medical journal Magnetic Resonance in Medicine concludes that Spin-Density Projection-Assisted MRI measurement of liver iron concentration (LIC) is “a reliable and accurate method for estimation of LIC that is suitable for diagnosis and management of patients with iron overload.”
The study, entitled “Multicenter validation of spin-density projection-assisted R2-MRI for the non-invasive measurement of liver iron concentration,” examined data from a group of 233 beta-thalassemia major patients in the Middle East. Among its findings, the authors state that Spin-Density Projection-Assisted R2 MRI is “the only MRI technique that has been calibrated and validated across multiple scanners in patients of different ages, with different stages of liver fibrosis and grades of liver necroinflammation.”
The paper can be read in its entirety here.
The paper was authored by Tim G. St. Pierre, Amal El-Beshlawy, Mohsen Elalfy, Abdullah Al Jefri, Kusai Al Zir, Shahina Daar, Dany Habr, Ulrike Kriemler-Krahn and Ali Taher.